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November 2012 · Vol. 61, No. 11: 678-686

Ectopic pregnancy: Zero in on these lab and imaging clues

Quantitative β-hCG measurements and transvaginal ultrasound findings interpreted in light of a β-hCG “cutoff” can reliably guide clinical decisions.


Sahoko  H.  Little,  MD

Department of Family Medicine, University of Michigan, Ann Arbor
sahoko@med.umich.edu

Pamela  G.  Rockwell,  DO

Department of Family Medicine, University of Michigan, Ann Arbor

PRACTICE RECOMMENDATIONS

Administer a urine pregnancy test for women of childbearing age who present with abdominal pain or vaginal bleeding. C

Initiate quantitative beta-human chorionic gonadotropin testing and order transvaginal ultrasound for women with abdominal pain or vaginal bleeding and a positive urine pregnancy test, but no confirmation of intrauterine pregnancy by abdominal ultrasound. B

Refer hemodynamically stable patients with ectopic pregnancy for laparoscopic salpingostomy. For selected patients, an alternative is medical treatment with methotrexate. A

Strength of recommendation (SOR)

A Good-quality patient-oriented evidence

B Inconsistent or limited-quality patient-oriented evidence

C Consensus, usual practice, opinion, disease-oriented evidence, case series

The authors reported no potential conflict of interest relevant to this article.

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