Practical Strategies in the Management of Hypertriglyceridemia: The Role of Omega-3 Fatty Acids William Harris, PhD Interviewed by Stephen Brunton, MD Running Time: 22:16

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PROGRAM OVERVIEW:

Triglycerides (TG) are an important factor to consider when evaluating patients with coronary heart disease (CHD). To date, there has been minimal exploration of the controversial relation between TG and CHD. Until recently, dietary supplements were the only option for targeted treatment of elevated TG. Recent studies of omega-3 fatty acids (FAs) as dietary supplements and a prescription preparation show evidence that the latter provides definite benefits. Due to these recent findings, non-HDL cholesterol is becoming an important measurement in the management of CHD.

In this program, we will discuss the factors that constitute hypertriglyceridemia and the prevalence of this lipid disorder. Further, we will explore the relevant metabolic pathways and the inherited and environmental causes of hypertriglyceridemia.

This program includes a review of the evidence supporting the cardioprotective effect of omega-3 FAs, the effect of supplementation on serum lipids, and the dosage needed to alter serum TGs. Recent and upcoming studies of omega-3 acid ethyl esters are highlighted, and the mechanism of action by which omega-3 FAs operate on TG is explained.

ACCREDITATION:

This activity has been planned and implemented in accordance with the Essentials and Standards of the Accreditation Council for Continuing Medical Education through the joint sponsorship of Texas Academy of Family Physicians and Primary Care Education Consortium. The Texas Academy of Family Physicians is accredited by the ACCME to provide continuing medical education for physicians.

The Texas Academy of Family Physicians designates this educational activity for a maximum of .50 AMA PRA Category 1 Credits™. Physicians should only claim credit commensurate with the extent of their participation in the activity.

This activity has been reviewed and is acceptable for a maximum of up to .50 Prescribed credits by the American Academy of Family Physicians.

Sponsored by the Texas Academy of Family Physicians and Primary Care Education Consortium and supported by an educational grant from Reliant Pharmaceuticals.